Types of Clinical Trials
Clinical trial phases
- Phase I
Assess patient safety. The first step in testing a new drug or treatment on patients is to determine its safety, dosage and side effects. This phase usually involves small groups of patients.
- Phase II
Assess treatment effectiveness. The new drug or treatment is tested on a larger group of patients. Researchers continue to test the safety of the drug or treatment while evaluating its effectiveness.
- Phase III
Compare new treatments to standard therapies. Researchers determine if the new treatment is better than, the same as or worse than a commonly used treatment. Some patients receive the new treatment while others receive the commonly used treatment. This phase may involve hundreds or thousands of patients at multiple locations.
- Phase IV
Long-term safety and effectiveness. These studies take place once the new treatment is approved for standard use and put on the market. We do not conduct phase IV trials at our hospital.