Types of Blood and Marrow Transplant

Benefits of haploidentical transplant

For patients with fewer donor options and without a full match, a half-matched related – or haploidentical – transplant can mean a cure.

  • With more donors available, nearly every patient can find a match
  • Shorter wait times improve patient outcomes, especially for patients with aggressive cancers
  • Transplants can be done in 2-3 weeks, instead of several months
  • Above all, more patients live

We provide different types of bone marrow and peripheral blood stem cell transplants. The transplanted cells renew your blood supply after chemotherapy and/or radiation therapy.

Blood-forming stem cells, or hematopoietic cells, are in bone marrow. Peripheral blood stem cells are in the bloodstream. These cells can develop into red blood cells, white blood cells or platelets, which help the blood to clot.

The type of transplant you get depends on your specific diagnosis, stage of disease, overall health, current physical condition and age. Some types of blood and marrow transplant are outpatient procedures.

Types of transplants

  • Autologous
    We collect your healthy bone marrow stem cells and freeze them in liquid nitrogen until it's time for your transplant. Using your cells greatly reduces the risk of complications.
  • Allogeneic
    Stem cells come from a donor whose tissue matches yours. Potential donors are siblings, close relatives or matched unrelated donors.

    Allogeneic transplants increase the risk of complications. These include graft-versus-host disease, where the donor's immune cells destroy the patient's tissue. Medications can prevent and treat GVHD.

    We are designated by the National Marrow Donor Program as a matched unrelated donor transplant center. Types of allogeneic transplants are:
    • Syngeneic
      Because donor and recipient are identical twins with the same genes, the tissues match perfectly. There are fewer complications.
    • Cord blood
      Depending on your condition, you may have an umbilical or cord blood transplant. This type of transplant may not require a perfect tissue match.
    • Nonmyeloablative
      Combining less toxic chemotherapy treatment and blood stem cell transplant takes advantage of the donor's immune system to control a patient's disease. This is called the graft-versus-tumor effect. The donor's white blood cells launch an immune response to destroy the cancer cells in the recipient.
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