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Maternal-Fetal Medicine

Happy pregnant mom

The best care for you and your baby starts at the beginning. At our world-class clinical and research facility, we are dedicated to the goal of improving the lives of babies in the womb and providing hope to their families.

Designed to be the premier maternal-fetal-medicine resource in the region for care and support of mothers and unborn babies, we are your first choice for the evaluation and treatment of fetal abnormalities, customized care plans and improved patient outcomes. Our team of board-certified, fellowship-trained maternal-fetal-medicine doctors offers more than 100 years of combined experience.

About maternal-fetal medicine

Maternal-fetal-medicine specialists at The University of Kansas Health System offer comprehensive medical care for expectant mothers. Our advanced maternal and fetal care team, including maternal-fetal medicine specialists or perinatologists, collaborate to provide a complete range of services to help detect and treat fetal abnormalities early in pregnancy. Many of our advanced diagnostic tests and treatments were developed here, and in many cases, we are the only facility in the Kansas City region to provide these complex services.

We offer a variety of appointment types. Learn more or call 913-588-1227 to schedule now.

Maternal-fetal medicine FAQ

  • For this evaluation, an ultrasound is performed between 11 and 13 weeks. Evaluation of the developing fetal nuchal translucency thickness (skin thickness at the back of the fetal neck), nasal bone and blood flow measurements can be used to calculate a risk for common chromosome abnormalities. Information regarding the results of the ultrasound are calculated, and patients are counseled regarding the results at the time of the appointment.


  • First trimester ultrasound

    First trimester ultrasound screening is designed to evaluate for several chromosome problems, including Down syndrome. The ultra-sonographer will look at several different structures on your baby, including nuchal translucency (measurement of the amount of fluid underneath the skin at the back of the baby's neck), presence of the bone in the baby's nose and blood flow through a vessel called the ductus arteriosus. They also look at blood flow through the tricuspid valve in the baby's heart. Abnormalities in these specific areas can be associated with chromosome problems like Down syndrome.

    First trimester biochemical

    This is additional blood testing that looks at several pregnancy hormones in your blood. This blood testing may detect additional cases of Down syndrome, trisomy 13 or trisomy 18. This is an optional screen that can be performed in the first trimester.

    Second trimester maternal serum

    Second trimester maternal serum screening is designed to evaluate the risk for several chromosome problems, such as Down syndrome. It can also assess the risk for neural tube defects, such as spina bifida. This blood test can be performed between 15 and 22 weeks of pregnancy. This test in not recommended if a patient has already had screening in the first trimester of pregnancy.

    Noninvasive prenatal

    Additional screening evaluating cell-free DNA from the placenta in a mother's blood is available in certain circumstances.

  • In the second trimester, between 16 and 20 weeks of pregnancy, a blood test to measure the amount of alpha fetoprotein in the mother’s blood may be offered. This test screens for neural tube defects, such as spina bifida. Women who have normal first trimester screening may opt for this test only. This screening is included in the second trimester serum screening.


  • If family history or screening tests indicate an increased risk for a disorder, amniocentesis may be used to provide diagnosis for the condition. This involves the removal of a small amount of amniotic fluid from the amniotic sac under the guidance of ultrasound. There is a small risk to the pregnancy, but it is often much less than the risk of the condition of concern. Prior to such testing, genetic counseling is offered to understand the risks, benefits and alternatives to invasive testing.


  • In the past, all women over 35 were offered invasive prenatal testing such as amniocentesis or chorionic villus sampling, also known as CVS, to diagnose chromosome abnormalities like Down syndrome. While it is true that the risk for chromosome abnormalities increases with maternal age, most babies with chromosome abnormalities are born to women under 35. This is because women under 35 are having many more babies, and chromosome abnormalities can happen at any age. Therefore, maternal age is a poor predictor for fetal chromosome abnormality.

    Recent advances in prenatal testing can evaluate the risk for common chromosome abnormalities without any risk to the pregnancy. Invasive prenatal testing should be based on the results of these screening tests, parental concern and other personal factors rather than just age alone.


Maternal-fetal-medicine services

The comprehensive services offered by our physicians help not only to accurately test and diagnose, but also to provide leading-edge maternal and fetal medicine treatment. Services include a full range of fetal diagnostic tests and treatment options provided by renowned experts who are dedicated to improving mother-to-baby womb care.

We welcome community-based collaboration, routinely providing telephone and email referring provider consultations. Currently, we have 6 practices located in the greater Kansas City area: Kansas City, Kansas, Overland Park, St. Joseph, Gladstone, Lawrence and Topeka.

  • Our team offers many of the most innovative, leading-edge approaches in fetal medicine. These include 3D ultrasound, multivessel fetal Doppler (to monitor the fetal oxygen status) and first-trimester fetal echocardiography.

    Our physicians, certified in first-trimester nuchal translucency screening, provide reliable, noninvasive ultrasound screening for Down syndrome and other chromosomal abnormalities. We provide a full range of diagnostic tests, including comprehensive first-trimester wellness examinations. This includes a thorough history and physical, along with tests to examine:

    • Nuchal translucency
    • Nasal bone
    • Ductus venosus
    • Tricuspid regurgitation
    • Biochemical markers

    By identifying fetal abnormalities as early as possible, we can give you the best opportunity for treatment before birth as well as proper care after birth.

    Additional fetal diagnostic tests we offer include:

    • Amniocentesis 15 weeks to term
    • Diagnostic amnioinfusion
    • Diagnosis of fetal hypoxia or growth restriction
    • Chorionic villus sampling at 11-14 weeks
    • Endovaginal ultrasound
    • Fetal biopsy
    • Fetal blood sampling – cardiocentesis
    • Fetal MRI
    • Fetal echocardiogram
    • Fetoscopy
    • Invasive testing
    • Maternal and fetal blood flow studies
    • Molecular biologic testing for single gene disorders
    • Multiformat fetal echocardiogram
    • PCR (polymerase chain reaction) for the diagnosis of fetal infection, blood type, rH, etc.
    • Preterm birth risk screening
    • Rapid karyotype
    • Targeted 2D and 3D ultrasound imaging
  • The birth of your baby is a special event. At The University of Kansas Health System, our labor and delivery services bring you evidence-based, safe and family-centered maternity care in a comfortable, state-of-the-art setting. To tour our labor and delivery suites, call 913-588-1227.

    For babies who need extra care, physicians in the neonatal intensive care unit (NICU) work with obstetricians, perinatologists (physicians who specialize in high-risk pregnancies), family physicians, pediatric specialists and surgeons. Together, they provide an ongoing continuum of care for you and your baby.

  • The advanced fetal care team offers a first-trimester wellness exam to help parents-to-be make sure they’re doing everything they can to have a healthy baby. The exam includes:

    • Discussion about your medical and family history
    • A complete physical exam
    • Detailed ultrasound
    • Blood sample

    This 30- to 45-minute screening can detect chromosome abnormalities, malformations or birth defects, heart defects and the presence of twins. It also may help physicians gauge your risk of preterm birth. If any of these complications is suspected, you may receive additional tests, including a follow-up screening at 20 weeks.

    Our team of renowned physicians and researchers has performed more than 3,000 successful intravascular fetal procedures. Among these procedures are hundreds of lifesaving fetal blood or platelet transfusions, drainage procedures, intrauterine shunt catheters, laser therapy for twin-to-twin transfusion syndrome and other fetal surgeries.

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